Chris Bisson was born in Wythenshawe on 21 July 1975 and is the stepson of Granada television executive and presenter, Eamonn O'Neal. Chris first appeared on television as J.J. in Children's Ward in 1990. He went on to appear in Prime Suspect and Holby City, but he is most recognised for his roles as Saleem Khan in East is East, Vikram Desai in Coronation Street, Kash Karib in Shameless and Jai Sharma in Emmerdale. He also appeared in the second series of I'm a Celebrity, Get Me Out of Here!.
He appeared in Perfect Day: The Wedding (2005), Perfect Day: The Funeral (2006; Channel Five) and the feature film Stepdad (filmed in February 2007). He participated in the Channel 4 Documentary Empire's Children (2007) tracing his paternal heritage to Trinidad in the West Indies. His recent television appearances have been on the Valentine's Day 2009 episode of Casualty, and on the latest series of Hotel Babylon.
He returned to Shameless in April 2009 for only one episode. In September 2009, Bisson joined the cast of Emmerdale as part of the newly cast Sharma family. He and his family appeared on celebrity family fortunes in October 2011 winning £10,000 for charity.